A New Approach to Correcting Autism

Claudia Wallis:

The causes of autism remain largely shrouded in mystery, but there are some types of the disorder that can be traced to specific gene defects. The most common of these — responsible for roughly 5% of autism cases — is a flaw in the X chromosome that causes a condition known as Fragile X Syndrome. Because the defect has been studied on a molecular level, it provides a unique window into understanding autism — and treating it. And that is why a paper published in this week's issue of the journal Neuron is bound to generate excitement, even though the work was done in rodents. It shows that wide-ranging symptoms of Fragile X, which include epilepsy, impaired mental functioning, aberrant brain structure and other abnormalities, can be reversed. The work, researchers say, holds enormous promise for humans with Fragile X and probably for other forms of autism as well.

Posted by Jim Zellmer at December 22, 2007 12:00 AM
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