So why not just answer the questions?
Retraction Watch says it is “tracking retractions as a window into the scientific process.” Among the retractions it watches are NEJM’s.
On January 10, 1980, NEJM published a letter from Jane Porter and Hershel Jick, M.D., of the Boston Collaborative Drug Surveillance, Program Boston University Medical Center, Waltham, Massachusetts, under the headline, “Addiction Rare in Patients Treated with Narcotics.”
The letter said, “Recently, we examined our current files to determine the incidence of narcotic addiction in 39,946 hospitalized medical patients who were monitored consecutively. Although there were 11,882 patients who received at least one narcotic preparation, there were only four cases of reasonably well documented addiction in patients who had no history of addiction. The addiction was considered major in only one instance. The drugs implicated were meperidine in two patients, Percodan in one, and hydromorphone in one. We conclude that despite widespread use of narcotic drugs in hospitals, the development of addiction is rare in medical patients with no history of addiction.”
